Research | Publications

Research | Publications

Here you will find research results and publications on our most important topics.

Visual Feedback and Postural Control in Multiple Sclerosis
Abstract: As people with multiple sclerosis (pwMS) manifest heterogeneous demyelinating lesions
that could affect somatosensory or vestibular ways, visual stimulus as feedback could be especially
relevant to achieve postural control. This has clinical importance for the development of preventive
measures and rehabilitation therapies in order to avoid falls and accidents in this group. In our study,
we objectively evaluated the influence of visual feedback on the stabilization of balance in pwMS
versus healthy controls (HC) and its potential utility in clinical evaluation. Static posturography tests
were performed in 99 pwMS and 30 HC. Subjects stood on a force platform with open and closed
eyes. During this procedure, three balance parameters were obtained for both vision conditions:
average sway, average speed, and average speed of sway. Neurostatus-Expanded Disease Disability
Score (EDSS) and Multiple Sclerosis Functional Composite (MSFC) were performed in parallel as
well. A two-way mixed repeated measures ANCOVA, controlling for sex and age, was performed
to evaluate the effect of vision, MS diagnosis, and the interaction of both in static posturography
parameters. The difference between both closed and open eyes conditions was calculated for each
parameter and further analyzed according to MS-relevant clinical variables. The magnitude of the
vision effect differed between pwMS and HC as a significant interaction between the vision and the
MS diagnosis in the delineated area (p < 0.001) and average speed of sway (p = 0.001) was seen.
These parameters had a greater increase in pwMS than in HC after closing eyes. For the average
sway, a significant main effect of vision was present (p = 0.047). Additionally, the differences obtained
between open and closed eyes conditions assessed with the delineated area and average speed of sway
were moderately correlated to the assessed clinical tests EDSS (r = 0.405 and r = 0.329, respectively)
and the MSFC (r = −0.385 and r = −0.259, respectively). In our study, pwMS were more dependent
of visual feedback than HC to maintain postural control. This easy and short evaluation by static
posturography could support the development of targeted preventive measures and interventions
in pwMS
Research area: Balance | Coordination
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Visual Feedback and Postural Control in Multiple Sclerosis
Kostenlose Vorschau
Abstract: As people with multiple sclerosis (pwMS) manifest heterogeneous demyelinating lesions
that could affect somatosensory or vestibular ways, visual stimulus as feedback could be especially
relevant to achieve postural control. This has clinical importance for the development of preventive
measures and rehabilitation therapies in order to avoid falls and accidents in this group. In our study,
we objectively evaluated the influence of visual feedback on the stabilization of balance in pwMS
versus healthy controls (HC) and its potential utility in clinical evaluation. Static posturography tests
were performed in 99 pwMS and 30 HC. Subjects stood on a force platform with open and closed
eyes. During this procedure, three balance parameters were obtained for both vision conditions:
average sway, average speed, and average speed of sway. Neurostatus-Expanded Disease Disability
Score (EDSS) and Multiple Sclerosis Functional Composite (MSFC) were performed in parallel as
well. A two-way mixed repeated measures ANCOVA, controlling for sex and age, was performed
to evaluate the effect of vision, MS diagnosis, and the interaction of both in static posturography
parameters. The difference between both closed and open eyes conditions was calculated for each
parameter and further analyzed according to MS-relevant clinical variables. The magnitude of the
vision effect differed between pwMS and HC as a significant interaction between the vision and the
MS diagnosis in the delineated area (p < 0.001) and average speed of sway (p = 0.001) was seen.
These parameters had a greater increase in pwMS than in HC after closing eyes. For the average
sway, a significant main effect of vision was present (p = 0.047). Additionally, the differences obtained
between open and closed eyes conditions assessed with the delineated area and average speed of sway
were moderately correlated to the assessed clinical tests EDSS (r = 0.405 and r = 0.329, respectively)
and the MSFC (r = −0.385 and r = −0.259, respectively). In our study, pwMS were more dependent
of visual feedback than HC to maintain postural control. This easy and short evaluation by static
posturography could support the development of targeted preventive measures and interventions
in pwMS
Evaluation of the arthroscopic Broström-Gould procedure for the treatment of chronic instability of the upper ankle joint (2021-10 dissertation).
Kostenlose Vorschau
The ankle joint provides the connection between the lower leg and the foot. It transmits the weight
and the axially acting forces of the upper half of the body via the talus to the hindfoot, midfoot and forefoot.
Stability and functionality are ensured by a complex interplay of bones, muscles and capsule/ligamentous apparatus.
ligamentous apparatus. The lateral capsule/ligamentous apparatus plays a particularly important role in the
ligamentous apparatus in interaction with the peroneal musculature. These structures are therefore at high risk of injury.
Acute external ligament injury is one of the most common injuries and thus a daily challenge for every surgeon.
challenge for every surgeon. Despite the good to very good healing rates, there is a risk of
chronicity in 20-40% of patients.
The consistent further development and establishment of new treatment paths is therefore imperative.
The application of early functional concepts with physiotherapeutic exercise to restore stability and functionality must be
to restore stability and functionality in order to avoid re-injury or chronicity.
or chronification.
If the presence of symptomatic chronic upper ankle instability is clinically confirmed and
instability of the upper ankle, after all conservative measures have been exhausted, surgical treatment is
a surgical treatment tailored to the individual patient. There are a number of open and increasingly also arthroscopic
arthroscopic surgical procedures.
The present study deals with an arthroscopic modification of the surgical method according to
Broström-Gould.

The MediBalance PRO was used analytically in the context of the dissertation (p. 35 ff.).
Balance Testing in Multiple Sclerosis-Improving Neurological Assessment With Static Posturography?
Kostenlose Vorschau
Balance problems can severely limit the quality of life for people with Multiple Sclerosis (pwMS) already in the early stages of the disease. PwMS are usually assessed with the Expanded Disability Status Scale (EDSS), which includes a Romberg test for assessing balance. As the EDSS assessments are subjective to the examining neurologist, the postural stability of pwMS could be objectively quantified by implementing static posturography to detect balance problems and address preventive medical care
Validity and Reliability of Limits-of-Stability Testing: A Comparison of 2 Postural Stability Evaluation Devices
Kostenlose Vorschau
Keywords: postural control, balance, measurements
An Official Journal of JAT
www.nata.org/jat
TECHNICAL NOTE
The full article can be obtained here:
https://meridian.allenpress.com/jat/article/46/6/600/110742/Validity-and-Reliability-of-Limits-of-Stability

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